Temporal characterization of gap junction communication between tenocytes under tensile strain in vitro
نویسنده
چکیده
Tendons are mostly composed of collagen fibers and transmit forces from muscle to bone. Tenocytes are cells in tendon that produce main constituent of tendon such as type I collagen, and are linked each other via gap junctions at cell-cell junctions. Most cells in normal tissues generally communicate via gap junction. For example, ion and small molecule movements through the gap junction channels occur by passive diffusion. It has been shown that gap junction intercellular communication (GJIC) is essential in mechanosensitive response of tenocytes (1) .
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